Piercell

Product

LEAP™, is a non-viral transfection kit that delivers DNA directly into the nuclei of target cells using nano-needle arrays. It allows an extremely efficient transfection of even the hardest-to-transfect cells such as Primary cells, Stem Cells, Neurons and White Blood Cells in unprecedented speed and ease.

 

Non Viral

LEAP™ is non-viral and hence easier and safer to work with. Although  it is currently licensed for research only, in the future it may enable shorter regulatory path for cell therapy clinical trials.

 

FAST

LEAP™ shortens the time between plasmid synthesis and expression by:

  • Enabling transfection right after plasmid synthesis, saving weeks of virions preparation
  • Delivering plasmids directly into the nuclei, saving waiting time for cell division 

 

Easy to use

Using LEAP™ involves a rapid, 3-step protocol:

  • Add your DNA plasmids into  the  LEAP™   test tube
  • Add your target cells and  centrifuge in a standard swinging bucket centrifuge
  • Flip the LEAP™ test tube over and centrifuge again

 

Efficiency and viability

Leaping over the cytoplasm makes the LEAP™ an extremely efficient transfection tool for even the hardest-to-transfect cells such as Primary cells, Stem Cells, Neurons and White Blood Cells. The nano-scale needle diameter and the patented test tube enable expression  without causing damage to the cells.

Non-Viral Methods for Stable Transfection:

Non-viral transfection of primary cells, hematopoeitic stem cells, neurons and other hard to transfect cells